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Characteristic
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Univariate analysis
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Multivariate analysis
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|---|
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HR
|
95% CI
|
P value
|
HR
|
95% CI
|
P value
|
|---|
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Age (years)
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≤ 45 vs. 46–59 vs. ≥ 60
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1.002
|
0.990–1.015
|
0.720
|
–
|
–
|
–
|
|
Sex
|
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Female vs. male
|
0.769
|
0.607–0.975
|
0.030
|
0.865
|
0.680–1.101
|
0.239
|
|
Smoking status
|
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Yes vs. no
|
1.176
|
0.944–1.465
|
0.149
|
–
|
–
|
–
|
|
Drinking status
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Yes vs. no
|
1.195
|
0.922–1.548
|
0.178
|
–
|
–
|
–
|
|
Weight loss rate
|
|
0 vs. > 0% to ≤ 5.0% vs. > 5.0% to ≤ 10.0% vs. > 10.0%
|
1.168
|
1.047–1.302
|
0.005
|
1.118
|
1.000–1.251
|
0.060
|
|
BMI (kg/m2)
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< 18.5 vs. ≥ 18.5 to < 25.0 vs. ≥ 25.0
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0.970
|
0.779–1.207
|
0.784
|
–
|
–
|
–
|
|
Tumor location
|
|
Upper vs. middle vs. lower
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0.932
|
0.767–1.134
|
0.483
|
–
|
–
|
–
|
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Tumor grade
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G1 vs. G2 vs. G3
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1.489
|
1.271–1.745
|
< 0.001
|
1.373
|
1.164–1.621
|
< 0.001
|
|
pT category
|
|
T1 vs. T2 vs. T3 vs. T4
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1.642
|
1.308–2.062
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< 0.001
|
1.257
|
0.982–1.611
|
0.070
|
|
pN category
|
|
N0 vs. N1 vs. N2 vs. N3
|
1.820
|
1.594–2.079
|
< 0.001
|
1.474
|
1.181–1.839
|
0.001
|
|
pTNM stage
|
|
Stage I vs. stage II vs. stage III
|
2.270
|
1.832–2.813
|
< 0.001
|
1.237
|
0.872–1.754
|
0.233
|
|
Complications
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|
None vs. anastomotic leakage vs. pneumonia vs. others
|
1.118
|
0.961–1.299
|
0.148
|
–
|
–
|
–
|
|
T2DM
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|
With T2DM vs. without T2DM
|
0.896
|
0.719–1.116
|
0.326
|
–
|
–
|
–
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- ESCC esophageal squamous cell carcinoma, BMI body mass index, T2DM type 2 diabetes mellitus, pT pathological tumor, pN pathological node, pTNM stage pathological tumor/node/metastasis, HR hazard ratio, 95% CI 95% confidence interval, – no comparison
